Description
We are now recruiting a Clinical Research Fellow to join the Reilly research group in the CNMD. The Reilly group has developed a quantitative calf muscle Fat Fraction MRI protocol, the most responsive outcome measure (OM) in multiple forms of Charcot Marie Tooth disease. Technology advances using artificial intelligence in sequence acquisition and analysis mean we can now develop our protocol to be more accurate, reliable, sensitive and faster.
This study will aim to optimise our MRI OM using these technological advances, set up six other CMT trial-ready centres across the UK, and investigate the UK CMT landscape.
You will support this study while working closely with our physicists, trial coordinators, data managers, geneticists, bioinformaticians, and clinicians. As part of the role, you will receive comprehensive training in all aspects of neuropathies, including clinical evaluation, clinical outcome measures, MRI fat-fraction analysis, and genetic analysis.
You will assist in recruiting and clinically evaluating patients for the MRI studies at UCL, as well as be trained to use the AI programme for assessing fat-fraction results from MRI scans. In addition, you will help coordinate with the six other UK centres to collate and manage the data collected across all sites. You will also help study the genetic architecture of CMT in the UK. As the main investigator into the study on the frequency and types of CMT in the UK, you will liaise with PIs and trial coordinators in the other six UK sites.
This post is suitable for a trainee who wishes to develop expertise in neuropathies, especially inherited neuropathies. There may also be the option to enrol for a PhD focused on MRI, genetics, or both aspects of the study.
An Honorary Clinical contract will be sought from UCLH NHS Trust, for which a DBS check will be required.
The post is available from 01 August 2026 (this start date is flexible) and is funded by Muscular Dystrophy UK for three years in the first instance, although we would also be happy to consider trainees looking for a one- or two-year clinical research fellowship in neuropathy.
Requirements
About you
At the time this post commences, you must be a registered Medical Practitioner licenced to practise in the UK with good knowledge of confidentiality/GDPR, Good Clinical Practice, the NHS clinical governance framework, and clinical audit experience. You’ll have the ability to provide clinical supervision, communicate effectively and compassionately with patients from a diverse range of backgrounds and with diverse clinical and social needs, and demonstrate enthusiasm and ability to “go the extra mile” for patients and clinical care.
Experience of having worked in the NHS and in clinical neurology, completion of CMT/IMT training and MRCP, and excellent presentation skills are desirable.
This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.
