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Arbor Biotechnologies
Cambridge, Massachusetts, United States (on-site)
3 days ago

Description

The Senior Research Associate/Research Associate will support our LNP formulation pipelines and in vitro/in vivo preclinical requirements through the design and execution of experiments to help screen and produce various non-viral formulations enabling the encapsulation of various RNA entities. This candidate will also help support various characterization assays for the various formulations as needed. The ideal candidate for this position will be a motivated and proactive individual with a passion for nanomedicinal/LNP formulations and processes. The applicant should have strong wet laboratory, communication and collaboration skills preferably with a background in the appropriate formulation deliverables. This role will have no supervisory responsibilities and will report to the Principal Scientist, Non-Viral Gene Therapy.

Key Responsibilities:

  • Assist in the design and execution of experiments to screen, produce, characterize, and optimize LNP formulations for both in vitro and in vivo delivery of gene editing entities.
  •  Support the generation of preclinical LNP test materials or other formulation/drug substance characterization lots
  • Perform routine analytical testing to characterize formulations as needed
  • Adhere to highest standards of data integrity through thorough and detailed electronic lab notebooks and documentation records
  • Adhere to all laboratory safety requirements and procedures
  • Assist in maintaining general laboratory functionality associated with the gene therapy and delivery group, including lab equipment maintenance and the ordering and receiving of lab supplies.
  •  Develop and maintain protocols, operational processes, and best practices.
  • Communicate results at team meetings, contribute to project and experiment planning

Preferred Qualifications:

  • BS/MS or equivalent in Chemical/Biomedical/Biochemical Engineering, Bioengineering, Chemistry, Biochemistry, Pharmaceutical Sciences or a related field
  • 1-3 years of hands-on experience with lipid nanoparticles systems for RNA delivery in an industry or industry-like setting.
  • Knowledge of process development/scale-up or screening of LNP Formulations or nucleic acid/lipid chemistry is preferred
  • Innovative and science-driven; a self-starter possessing high scientific rigor.
  • Collaborative and an excellent communicator 

Our Values:

Our values govern the work we do at Arbor, and we’re hoping that they resonate as strongly with you as they do with us!

  • Astonishingly Connected: The best work happens when we do it together. At Arbor, we believe strong, clear communication is crucial to our success and emboldens collaboration in all of us.
  • Our People are Gems: And we treat each other as such by celebrating our growth and development. We invest in our team and encourage everyone to have both a learners mindset and a willingness to teach others.
  • Remarkably Mighty: You'll be intrigued when you take a closer look at Arbor. We approach our work with integrity and thoughtfulness. We are brave, which leads us to take smart risks and make bold discoveries.
  • Authenticity is Encouraged: From eating cheese puffs with chopsticks, to doing cartwheels on our balance beam, we're all about embracing your true self and showing up as you really are. Our differences make us extraordinary.

About Arbor:

At Arbor, we are discovering, developing and making available to all patients the next-generation of genetic medicines. We are disrupting the field through our proprietary discovery engine to develop a portfolio of differentiated genetic editing and delivery capabilities. We have an unencumbered portfolio of multiple CRISPR based genetic modifiers that can be tailored to correct the underlying pathology of each genetic disease. Our pipeline of genetic medicines will focus on bringing cures to all patients with genetic disease.

We seek highly-motivated individuals with the dedication, integrity, and creative spirit needed to thrive in an innovative company. Working at Arbor offers a unique opportunity that combines the fast pace and growth opportunities of a startup with the intellectual rigor and creativity of academia. Our salaries are competitive, our benefits are generous, and our team is exceptional.

Arbor Biotechnologies is proud to be an inclusive workplace and an Equal Opportunity Employer.



Job Information

  • Job ID: 64580202
  • Workplace Type: On-Site
  • Location:
    Cambridge, Massachusetts, United States
  • Position Title: Research Associate/Senior Research Associate, Non-Viral Gene Therapy
  • Company Name For Job: Arbor Biotechnologies
  • Job Function: Biochemistry,
    Biology,
    Other / Not Listed
  • Job Type: Full-Time
  • Job Duration: Indefinite
  • Required Travel: None
Cambridge , Massachusetts , United States

Arbor Biotechnologies is a venture-backed startup based in Cambridge, MA, composed of a small team of scientists and engineers pushing the boundaries of discovery at the intersection of computer science and biotechnology. Using our diverse backgrounds ranging from machine learning to genome engineering to protein biochemistry, we are building a platform to uncover and characterize nature’s inventions on an unprecedented scale to generate impactful applications in human health and sustainability. We seek highly-motivated ...

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