Description
We are seeking highly motivated and talented post-doctoral scientists to join the Munger Lab and investigate the mechanisms by which Human Cytomegalovirus (HCMV) manipulates cellular processes to facilitate infection. Our laboratory is located in the Department of Biochemistry & Biophysics at the University of Rochester Medical Center, Rochester, NY.
Projects will explore the mechanisms through which specific viral gene products: 1) modulate histone acetyl-transferase activities to regulate cellular gene expression; 2) target cellular metabolism to support infection; and 3) attenuate anti-viral signal transduction.
Key Responsibilities:
-Design and execute experiments to investigate HCMV-host interactions.
-Utilize a range of cutting-edge techniques, including:
Metabolomics, proteomics, and RNA sequencing to profile cellular changes during infection.
-Chromatin profiling: Techniques such as Cut&Run and Cut&Tag to analyze epigenetic modifications and gene regulation.
-Present research findings at lab meetings, institutional seminars, and national/international conferences.
-Prepare manuscripts for publication in peer-reviewed journals.
-Mentor junior lab members and contribute to a collaborative research environment.
Requirements
Qualifications:
Ph.D. in Virology, Molecular Biology, Cell Biology, Biochemistry, or a related field.
Demonstrated expertise in molecular and cellular biology techniques.
Experience with 'omics' technologies (metabolomics, proteomics) or chromatin profiling (Cut&Run, Cut&Tag, CHIP-seq) is a significant advantage.
Excellent written and oral communication skills.
Ability to work independently and as part of a collaborative team.
A strong publication record commensurate with experience.
To Apply:
Interested candidates should submit a cover letter outlining their research interests and career goals, a curriculum vitae, and contact information for three professional references to Joshua_munger@urmc.rochester.edu
